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Taysha Gene Therapies, Inc. Common Stock (TSHA)

Price$5.95

Favorite Metrics

Price vs S&P 500 (26W)14.59%
Price vs S&P 500 (4W)29.01%
Market Capitalization$1.72B

All Metrics

Book Value / Share (Quarterly)$0.87
P/TBV (Annual)342.79x
Indicated Dividend (Annual)$0.00
Revenue Growth (3Y)57.53%
Cash Flow / Share (Quarterly)$-0.33
Price vs S&P 500 (YTD)6.45%
Net Profit Margin (TTM)-780.33%
EPS (TTM)$-0.34
10-Day Avg Trading Volume2.76M
EPS Excl Extra (TTM)$-0.34
EPS (Annual)$-0.34
ROI (Annual)-36.65%
Cash / Share (Quarterly)$1.12
Revenue Growth QoQ (YoY)171.27%
ROA (Last FY)-31.75%
Revenue Growth TTM (YoY)17.28%
EBITD / Share (TTM)$-0.37
ROE (5Y Avg)-3789.27%
Operating Margin (TTM)-782.50%
Cash Flow / Share (Annual)$-0.33
P/B Ratio6.98x
P/B Ratio (Quarterly)6.10x
Net Income / Employee (Annual)$-1
EV / Revenue (TTM)148.81x
Net Interest Coverage (TTM)-77.24x
ROA (TTM)-38.53%
EPS Incl Extra (Annual)$-0.34
Current Ratio (Annual)12.23x
Quick Ratio (Quarterly)12.10x
3-Month Avg Trading Volume2.93M
52-Week Price Return368.75%
Revenue / Employee (TTM)$0
Tangible BV / Share (Quarterly)$-0.26
P/S Ratio (Annual)176.37x
Asset Turnover (Annual)0.03x
52-Week High$6.04
EPS Excl Extra (Annual)$-0.34
CapEx CAGR (5Y)55.95%
26-Week Price Return18.58%
Quick Ratio (Annual)12.10x
13-Week Price Return23.46%
Total Debt / Equity (Annual)0.20x
Current Ratio (Quarterly)12.23x
Enterprise Value$1,454.337
Asset Turnover (TTM)0.04x
Book Value / Share Growth (5Y)-34.68%
Revenue / Employee (Annual)$0
Pretax Margin (Annual)-1115.27%
Cash / Share (Annual)$1.12
3-Month Return Std Dev80.91%
Net Income / Employee (TTM)$-1
ROE (Last FY)-44.14%
Net Interest Coverage (Annual)-65.37x
EPS Basic Excl Extra (Annual)$-0.34
Total Debt / Equity (Quarterly)0.20x
EPS Incl Extra (TTM)$-0.34
ROI (TTM)-45.60%
P/S Ratio (TTM)176.37x
Revenue / Share (Annual)$0.03
Tangible BV / Share (Annual)$0.02
Price vs S&P 500 (52W)338.92%
Year-to-Date Return9.09%
5-Day Price Return29.59%
EPS Normalized (Annual)$-0.34
ROA (5Y Avg)-73.00%
Net Profit Margin (Annual)-1115.27%
Month-to-Date Return34.23%
Cash Flow / Share (TTM)$-2.76
EBITD / Share (Annual)$-0.37
Operating Margin (Annual)-1130.65%
LT Debt / Equity (Annual)0.20x
ROI (5Y Avg)-153.51%
LT Debt / Equity (Quarterly)0.20x
EPS Basic Excl Extra (TTM)$-0.34
P/B Ratio (Annual)6.10x
Pretax Margin (TTM)-780.33%
Book Value / Share (Annual)$0.87
Price vs S&P 500 (13W)22.77%
Beta1.22x
Revenue / Share (TTM)$0.03
ROE (TTM)-56.64%
52-Week Low$1.13

Analyst Recommendations

Jan 2026
Feb 2026
Mar 2026
Apr 2026
4.25
4.25
4.25
4.25

Industry Peers — Biological Products(88)

SymbolP/S Ratio (TTM)Revenue Growth TTM (YoY)Gross Margin (TTM)EPS Growth (5Y)Price
TSHATaysha Gene Therapies, Inc. Common Stock
176.37x17.28%$5.95
AMGNAmgen Inc
5.13x9.95%73.30%2.93%$349.39
GILDGilead Sciences Inc
5.84x2.40%78.83%133.64%$138.55
ARGXargenx SE American Depositary Shares
12.46x89.56%150.91%$828.35
BNTXBioNTech SE American Depositary Share
8.75x-11.81%84.21%$102.12
BIIBBiogen Inc. Common Stock
2.60x2.22%75.69%-18.77%$176.02
MRNAModerna, Inc. Common Stock
11.02x-39.93%70.32%$54.68
NBIXNeurocrine Biosciences Inc
4.49x21.45%98.18%2.31%$128.41
EXELExelixis Inc
4.96x6.85%96.39%31.10%$44.38
TECHBio-Techne Corp.
7.60x1.64%66.60%-20.58%$57.36
HALOHalozyme Therapeutics, Inc.
5.74x37.55%83.62%22.89%$66.64

About

Taysha Gene Therapies develops AAV-based gene therapies for monogenic central nervous system diseases, targeting both rare and large patient populations. Its clinical-stage pipeline includes TSHA-102, a self-complementary AAV9 therapy delivered intrathecally for the treatment of Rett syndrome.