Castle Biosciences, Inc. Common Stock (CSTL) Stock Price

CSTLStock

$35.00+60.60%52W

Market Cap$1.07B

P/E47.31x

PEG Ratio—

Div yield—

Beta0.99

CSTL Share Price Chart

Favorite Metrics

Price vs S&P 500 (26W)-11.84%

Price vs S&P 500 (4W)37.05%

VGM Score61.39

P/E Ratio (Annual)47.31x

P/CF (Annual)14.68x

Book Value / Share (Quarterly)$15.41

P/TBV (Annual)2.97x

Indicated Dividend (Annual)$0.00

Revenue Growth (3Y)35.95%

Cash Flow / Share (Quarterly)$-0.02

Price vs S&P 500 (YTD)-25.92%

Gross Margin (TTM)77.26%

Net Profit Margin (TTM)-5.43%

EPS (TTM)$-0.65

10-Day Avg Trading Volume0.39M

EPS Excl Extra (TTM)$-0.65

Revenue Growth (5Y)40.62%

EPS (Annual)$-0.83

ROI (Annual)-5.02%

Gross Margin (Annual)79.37%

Net Profit Margin (5Y Avg)-21.98%

Cash / Share (Quarterly)$8.75

Revenue Growth QoQ (YoY)20.14%

EPS Growth (5Y)15.01%

P/E Normalized (Annual)47.31x

ROA (Last FY)-4.18%

Revenue Growth TTM (YoY)3.18%

EBITD / Share (TTM)$-0.71

ROE (5Y Avg)-8.05%

Operating Margin (TTM)-8.99%

Cash Flow / Share (Annual)$0.95

P/B Ratio2.01x

P/B Ratio (Quarterly)1.54x

Net Income / Employee (Annual)$-27,400

EV / Revenue (TTM)2.50x

Net Interest Coverage (TTM)-3.43x

ROA (TTM)-3.45%

EV / EBITDA (TTM)216.65x

EPS Incl Extra (Annual)$-0.83

Current Ratio (Annual)5.26x

Quick Ratio (Quarterly)5.58x

3-Month Avg Trading Volume0.42M

52-Week Price Return60.60%

EV / Free Cash Flow (Annual)31.52x

Revenue / Employee (TTM)$404,600

Tangible BV / Share (Quarterly)$12.64

P/S Ratio (Annual)2.74x

Asset Turnover (Annual)0.59x

52-Week High$44.28

Operating Margin (5Y Avg)-27.32%

EPS Excl Extra (Annual)$-0.83

CapEx CAGR (5Y)49.96%

Tangible BV CAGR (5Y)35.03%

26-Week Price Return-0.59%

Quick Ratio (Annual)4.99x

13-Week Price Return62.95%

Total Debt / Equity (Annual)0.02x

Current Ratio (Quarterly)6.04x

Enterprise Value$892.81M

Revenue / Share Growth (5Y)29.09%

Asset Turnover (TTM)0.64x

Book Value / Share Growth (5Y)-1.10%

Revenue / Employee (Annual)$389,800

Inventory Turnover (Annual)7.73x

Pretax Margin (Annual)-8.57%

Cash / Share (Annual)$10.09

3-Month Return Std Dev56.57%

Gross Margin (5Y Avg)80.12%

Net Income / Employee (TTM)$-22,000

EBITDA CAGR (5Y)17.49%

ROE (Last FY)-5.13%

Net Interest Coverage (Annual)-3.50x

EPS Basic Excl Extra (Annual)$-0.83

P/FCF (TTM)27.70x

Receivables Turnover (TTM)7.10x

EV / Free Cash Flow (TTM)200.32x

Total Debt / Equity (Quarterly)0.02x

EPS Incl Extra (TTM)$-0.65

Receivables Turnover (Annual)7.28x

ROI (TTM)-4.06%

P/S Ratio (TTM)2.64x

Pretax Margin (5Y Avg)-24.20%

Revenue / Share (Annual)$11.88

Tangible BV / Share (Annual)$12.87

Free OCF CAGR (5Y)40.79%

Price vs S&P 500 (52W)42.29%

Year-to-Date Return-13.96%

5-Day Price Return15.29%

EPS Normalized (Annual)$-0.83

ROA (5Y Avg)-7.04%

Net Profit Margin (Annual)-7.02%

Month-to-Date Return19.54%

Cash Flow / Share (TTM)$-2.39

EBITD / Share (Annual)$-0.21

Operating Margin (Annual)-12.44%

LT Debt / Equity (Annual)0.02x

P/CF (TTM)22.16x

ROI (5Y Avg)-8.04%

LT Debt / Equity (Quarterly)0.02x

EPS Basic Excl Extra (TTM)$-0.65

P/TBV (Quarterly)1.88x

P/B Ratio (Annual)2.41x

Inventory Turnover (TTM)8.58x

Pretax Margin (TTM)-5.37%

Book Value / Share (Annual)$15.86

Price vs S&P 500 (13W)60.16%

Net Margin Growth (5Y)-11.67%

Beta0.99x

P/FCF (Annual)33.35x

Revenue / Share (TTM)$11.75

ROE (TTM)-4.15%

52-Week Low$17.72

vGradeD

gGradeB

mGradeB

vgmGradeB

CSTL Earnings Surprise History

Q2 250.15est. -0.50

Q3 25-0.02est. -0.51

Q4 25-0.08est. -0.26

Q1 26-0.49est. -0.49

Q2 26-0.07est. -0.41

CSTL Analyst Recommendations

May 2026

Jun 2026

Jul 2026

Aug 2026

4.43

4.40

Industry Peers — Health Services(30)

Symbol	Value Score	Growth Score	Momentum Score	Price
CSTLCastle Biosciences, Inc. Common Stock	D	B	B	$35.00
NTRANatera, Inc. Common Stock	F	A	A	$336.71
LHLabcorp Holdings Inc.	C	D	B	$337.68
DGXQuest Diagnostics Inc.	C	D	B	$244.51
GHGuardant Health, Inc. Common Stock	F	A	A	$164.92
CAICaris Life Sciences, Inc. Common Stock	F	A	B	$28.01
RDNTRadNet, Inc. Common Stock	D	C	C	$76.86
BLLNBillionToOne, Inc. Class A Common Stock	F	F	C	$100.08
CELCCelcuity Inc. Common Stock	—	—	D	$92.27
GRALGRAIL, Inc. Common Stock	D	A	B	$82.54
VCYTVeracyte, Inc.	D	A	C	$44.04
CDNACareDx, Inc.	D	B	A	$50.80
PSNLPersonalis, Inc. Common Stock	F	D	A	$17.25
FTREFortrea Holdings Inc. Common Stock	B	F	A	$18.27
FRNMFreenome, Inc. Common stock	—	F	A	$13.99
LMRILumexa Imaging Holdings, Inc. Common Stock	C	C	B	$12.07
FLGTFulgent Genetics, Inc. Common Stock	C	D	C	$19.95
YDESYD Bio Limited Ordinary Shares	—	—	D	$4.68
BDSXBiodesix, Inc. Common Stock	D	B	A	$28.07
XGNExagen Inc. Common Stock	D	B	B	$7.60
PCSCPerceptive Capital Solutions Corp Class A Ordinary Shares	—	F	B	$11.95
BNRBurning Rock Biotech Limited American Depositary Shares	B	F	D	$9.80
SERASera Prognostics, Inc. Class A Common Stock	D	D	C	$2.18
MDXHMDxHealth SA Ordinary Shares	B	B	F	$0.79
ADVBAdvanced Biomed Inc. Common Stock	A	—	B	$9.18
AMSAmerican Shared Hospital Services	A	C	D	$1.47
ACONAclarion, Inc. Common Stock	—	B	D	$2.49
BGLCBioNexus Gene Lab Corp Common stock	B	F	F	$1.55
ACONWAclarion, Inc. Warrant	—	—	D	$0.03
EXASExact Sciences Corp	F	B	B	$0.00
YDESWYD Bio Limited Warrants	—	—	D	$0.36

About Castle Biosciences, Inc. Common Stock

Castle Biosciences is a molecular diagnostics company specializing in gene expression profile tests for oncology and gastrointestinal conditions. Its product portfolio includes DecisionDx-Melanoma and DecisionDx-SCC for skin cancer risk assessment, MyPath Melanoma for melanoma diagnosis, and TissueCypher for monitoring esophageal cancer progression. The company generates revenue by delivering diagnostic test reports to healthcare providers treating patients with dermatologic cancers, uveal melanoma, and Barrett's esophagus.